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Unusual presentation of more common disease/injury
Cardiac disease in a case of precursor B acute lymphoblastic leukaemia with eosinophilia(ALL/Eo)
  1. Mehrnaz Asadi Gharabaghi1,
  2. Pegah Aghajanzadeh1,
  3. Ghazal Zahedi1,
  4. Roghayyeh Borji1,
  5. Leila Derakhskan2,
  6. Roya Sattarzadeh2,
  7. Ramezanali Sharaifian3
  1. 1Department of Medicine, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
  2. 2Department of Cardiology, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
  3. 3Depatment of Haematology and Oncology, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran
  1. Correspondence to Dr Mehrnaz Asadi Gharabaghi, asadi_m{at}tums.ac.ir

Summary

Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy. However, it may rarely associate with eosinophilia. Patients with ALL associated with eosinophilia (ALL/ Eo) have a grave prognosis and higher incidence of cardiac complications compared to standard lymphoblastic leukaemia. Reports of ALL/Eo disclosed a few case with cardiac involvement early in the course of leukaemia. Here, the authors report a case of 13-year-old boy who presented with peripheral eosinophilia, chest pain and a large left ventricular mass early in the course of precursor B- cell ALL associated with eosinophilia. He received multi-agent chemotherapy but succumbed to death 25 days after chemotherapy due to a refractory cardio respiratory failure.

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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