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Unexpected outcome (positive or negative) including adverse drug reactions
Conservative treatment of a recto-urethral fistula due to savage HIFU for local recurrence of prostate cancer, 5 years after radical prostatectomy and external beam radiotherapy
  1. Luca Topazio,
  2. Claudio Perugia,
  3. Enrico Finazzi-Agro
  1. Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Provincia, Italy


Recto-urethral fistula is one of the most serious complications caused by high-intensity-focused ultrasound used as salvage treatment for recurrence of prostate cancer after brachytherapy or external beam radiotherapy (EBRT). We report the case of a recto-urethral fistula in a 68-year-old patient, who previously had undergone radical prostatectomy and EBRT for prostate cancer (pT3 N0 Mx). The fistula was treated conservatively by an indwelling Foley catheter, without the creation of an intestinal diversion. The fistula was assessed initially by a retrograde and a CT scan of the pelvis with contrast medium and reassessed periodically by means of retrograde urethrograms. To date, 24 months after this episode, no evidence of recurrence of the fistula has been found.

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