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Rare disease
Mesonephric adenocarcinoma of the uterine cervix and literature review
  1. Antonios Anagnostopoulos1,
  2. Stuart Ruthven2,
  3. Robert Kingston3
  1. 1Department of Obstetrics & Gynaecology, Countess of Chester, Chester, UK
  2. 2Department of Histopathology, Royal Liverpool University Hospital, Liverpool, UK
  3. 3Department of Gynaecology, Liverpool Women Hospital, Liverpool, UK
  1. Correspondence to Dr Antonios Anagnostopoulos, anagnost{at}


Mesonephric adenocarcinoma is a rare type of cervical cancer that derives from mesonephric remnants in the uterine cervix. To the best of our knowledge, this is the 34th case of mesonephric adenocarcinoma in adult women documented in the literature. We present an asymptomatic 64-year-old postmenopausal woman presenting with a suspicious-looking cervix as an incidental finding and diagnosed with a stage IB mesonephric adenocarcinoma of the cervix. This case was managed with radical hysterectomy, bilateral salpingoophorectomy and pelvic lymphadenectomy. The rarity of such cases imposes challenges on the management in terms of diagnosis, prognosis and therapeutic options.

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