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I read with interest the Case Report "Cervical lymphadenopathy:
metastasis of papillary carcinoma or ectopic thyroid tissue?", since I as
a pathologist recently faced a similar diagnostic situation with only
minimal thyroid tissue (less than 1 mm of size) in a cervical lymph node
(neck dissection due to squamous cell carcinoma of the head and neck
We classified the minimal amount of thyroid tissue as...
We classified the minimal amount of thyroid tissue as metastasis of a
papillary thyroid carcinoma due to a definitive papillary morphology of
the nuclei (nuclear grooves, Pseudoinclusions, ground glass appearance and
nuclear overlapping). A subsequent histological examination of the
surgical specimen of the entire thyroid gland revealed a papillary thyroid
carcinoma of 0.8 cm.
I would like to add one point to the discussion of this topic: even
only minimal thyroid tissue in a cervical lymph node allows the diagnosis
of metastasis (and not ectopic tissue) if a distinctive and classical
papillary nuclear morphology is present.
With kind regards,