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Learning from errors
Heparin-induced tumour bleed
  1. Venkatesh S Madhugiri1,
  2. Anita Mahadevan2,
  3. Sudheer Kumar Gundamaneni1,
  4. Manish Singh1
  1. 1Department of Neurosurgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India
  2. 2Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India
  1. Correspondence to Dr Venkatesh S Madhugiri, venkateshmadhugiri{at}


Patients with gliomas are at risk for deep vein thrombosis and thromboembolic events, and pharmacological prophylaxis may be indicated. This recommendation needs to be weighed against the risk of spontaneous haemorrhage from certain brain tumours. A patient, who was hemiparetic owing to a high-grade glioma and was started on heparin prophylaxis, developed a tumour bleed. The relevant issues are briefly discussed.

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