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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Management of a xeroderma pigmentosum case with oral findings in a dental setup
  1. Vanaja Reddy Banda1,
  2. Naveen Reddy Banda2,
  3. Ramesh Reddy3,
  4. Praveen Banda4
  1. 1Department of Oral Medicine and Radiology, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India
  2. 2Department of Pedodontics, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India
  3. 3Department of General Surgery, Videhi Institute of Medical Sciences, Bangalore, Karnataka, India
  4. 4Aspen Dental Clinic, Augusta, Maine, USA
  1. Correspondence to Dr Vanaja Reddy Banda, drreddybanda{at}


Xeroderma pigmentosum (XP) is heterogeneous group of disorder transmitted as autosomal recessive trait. It is characterised by photosensitivity, freckled pigmentation and premature skin ageing and malignant tumour development. The manifestations are due to a cellular hypersensitivity to ultraviolet light resulting from a defect in DNA repair. Multiple cutaneous neoplasms develop at a young age in persons with XP. Two important causes of mortality are metastatic malignant melanoma and squamous cell carcinoma (SCC). We report a case of XP in a 22 year-old male patient who developed SCC of lower lip with in a short period of 1 month.

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