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Extranodal lymphoma masquerading as carcinoma of the breast in an HIV-positive male patient
  1. Madhup Rastogi,
  2. Swaroop Revannasiddaiah,
  3. Rajeev Kumar Seam,
  4. Manoj Kumar Gupta,
  5. Manish Gupta
  1. Department of Radiation Therapy and Oncology, Regional Cancer Centre, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
  1. Correspondence to Dr Swaroop Revannasiddaiah, swarooptheone{at}gmail.com

Summary

This report describes a male patient infected with the HIV, with antiretroviral therapy (ART)-induced gynaecomastia. He presented with a right-sided breast mass which clinically resembled a carcinoma. A core biopsy suggested non-Hodgkin's lymphoma of diffuse large B cell histology. Also presented are his 18-fluoro-deoxy-glucose - positron emission tomography (FDG PET)-CT scan findings which showed a highly avid mass (standardised uptake value (SUV) 34.5) in his right breast. In spite of a very good clinical response after the first cycle of chemotherapy, his disease relapsed at multiple sites and progressed early. This case illustrates the aggressive course of HIV-associated extranodal lymphomas, and also highlights the issues concerning the use of ART and chemotherapy.

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