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Reminder of important clinical lesson
Unusual manifestations of Epstein-Barr virus infection in an 8-month-old male infant
  1. Peninnah Oberdorfer1,
  2. Kritsana Kongthavonsakul1,
  3. Taneeya Towiwat2,
  4. Nutchanun Klangkalya2
  1. 1Department of Pediatrics, Chiang Mai University, Chiang Mai, Thailand
  2. 2Department of Pediatrics, Khon Kaen Hospital, Khon Kaen, Thailand
  1. Correspondence to Dr Peninnah Oberdorfer, aoberdor{at}


Severe acute hepatitis is a rare complication of Epstein-Barr virus (EBV) infection. The authors report a case of an 8-month-old male infant who presented with subacute fever and jaundice. The physical examination showed hepatosplenomegaly and ecchymoses on his abdomen, chest wall and extremities. He received vitamin K therapy and prednisolone, and he recovered well without further complications or sequelae. Although severe acute hepatitis is a rare complication of EBV infection, clinicians should recognise this condition in order to provide a prompt treatment.

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