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Rare disease
Interstitial keratitis and sensorineural hearing loss as a manifestation of rheumatoid arthritis: clinical lessons from a rare complication
  1. Lennard YW Lee1,
  2. Mohammed Majid Akhtar2,
  3. Othman Kirresh3,
  4. Terence Gibson1
  1. 1Department of Rheumatology, Guy's & St Thomas's NHS Foundation Trust, London, UK
  2. 2Department of Cardiology, St Thomas’ Hospital, London, UK
  3. 3Epsom General Hospital, Epsom, UK
  1. Correspondence to Dr Mohammed Majid Akhtar, gogetmajid{at}


Cogan's syndrome or non-syphilitic interstitial keratitis with vestibule-auditory dysfunction is a serious and under-recognised complication of rheumatoid arthritis. It is an autoimmune condition characterised by inflammatory infiltrates on the cornea and extensive vestibulocochlear damage. If left untreated, patients progress to develop profound hearing loss. We present a case that was incorrectly diagnosed and treated as conjunctivitis by several emergency departments prior to being correctly recognised as Cogan's syndrome.

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