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Rare disease
Intracystic papillary carcinoma of breast: report of three cases and review of the literature
  1. Alhad R Dhebri1,
  2. Amna Ahmad2,
  3. Nigam Shah2,
  4. Pardeep K Arora1
  1. 1Department of Surgery, Tameside General Hospital, Ashton-under-lyne, UK
  2. 2Department of Pathology, Tameside General Hospital, Ashton-under-lyne, UK
  1. Correspondence to Alhad R Dhebri, adhebri{at}hotmail.com

Summary

Intracystic papillary carcinoma (IPC) of the breast is a rare malignant tumour, found mainly but not exclusively in elderly women. IPC may be asymptomatic or presents with a palpable mass or blood-stained nipple discharge. The tumour is encysted within a dilated duct with arborisation of the fibrovascular stroma and contains nodules of papillary carcinoma surrounded by a thick fibrous capsule. Frequently excisional biopsy is required for diagnosis. The mainstay of treatment is breast-conserving surgery or mastectomy. Sentinel node biopsy could be considered in invasive cases. Adjuvant radiotherapy (XRT) and/or endocrine therapy is considered in appropriate cases. Prognosis is excellent. We report three such cases of IPC, in elderly women, which were successfully treated.

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