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Pitfalls in the management of herpes simplex virus encephalitis
  1. Richard Tolulope Ibitoye1,
  2. Pamela Sarkar2,
  3. Satyan Rajbhandari3
  1. 1Department of Neurology, Royal Preston Hospital, Lancashire, UK
  2. 2Department of GUM/ID Medicine, St George's University Hospital, London, UK
  3. 3Department of Diabetes and Endocrinology, Chorley and South Ribble Hospital, Lancashire, UK
  1. Correspondence to Dr Pamela Sarkar, pam524sarkar{at}


We report a case of Herpes Simplex Virus Encephalitis (HSVE) with a fatal outcome of a patient in his 70s presenting to a local teaching hospital with fever and confusion. We highlight pertinent issues regarding diagnosis, investigation and management, and consider ways of improving clinical outcomes. Finally, we discuss the differential diagnoses of acute encephalitis and review the management of HSVE.

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