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Rare disease
Ectopic tubal choriocarcinoma: a rarity
  1. Seema Mehrotra1,
  2. Urmila Singh1,
  3. Madhumati Goel2,
  4. Shilpi Chauhan1
  1. 1Department of OB & GYN, CSMMU (formerly KGMU), Lucknow, Uttar Pradesh, India
  2. 2Department of Pathology, CSMMU (formerly KGMU), Lucknow, Uttar Pradesh, India
  1. Correspondence to Dr Seema Mehrotra, mehrotra.seema{at}


Herein, we present a case of tubal choriocarcinoma which was diagnosed initially as chronic ectopic pregnancy. During laparotomy we noticed a haemorrhagic friable mass in the left flank, adherent to the bowel. Left-sided salpingoopherectomy was performed. Serum β HCG (human chorionic gonadotropin) levels performed in the postoperative period were elevated. Histopathology demonstrated choriocarcinoma. She was given six cycles of chemotherapy (etoposide, methotrexate, actinomycin D-cyclophosphamide, vincristine/oncovine (EMA-CO) regime) and monitored by serial β HCG estimation. This case highlights the importance of undertaking histopathological examination of the tubal tissue in every patient who presents with ectopic pregnancy. This important diagnostic test prevents the potential of missing this rare and highly malignant disease which is otherwise curable in most instances.

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