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Unexpected outcome (positive or negative) including adverse drug reactions
Losartan-induced coronary artery spasm
  1. Johan Josefsson,
  2. Ole Fröbert
  1. Department of Cardiology, University Hospital of Örebro, Örebro, Sweden
  1. Correspondence to Johan Josefsson, johan.josefsson{at}orebroll.se

Summary

We report a case of coronary artery spasm documented with angiography in a patient with severe chest pain, electrocardiographic ST-segment elevations and highly elevated troponin I. Symptom onset was 15 min after the patient's first-ever intake of losartan. Although parts of the clinical presentation suggested allergy or anaphylaxis, laboratory testing did not support this.

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