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Unusual presentation of more common disease/injury
An unusual presentation of breast cancer in a very young woman
  1. Nicole P Sandhu1,
  2. Harry J Long2,
  3. Kiley J Johnson3,
  4. Amy C Degnim4
  1. 1Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
  2. 2Department of Medical Oncology, Mayo Clinic, Rochester, Minnesota, USA
  3. 3Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota, USA
  4. 4Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA
  1. Correspondence to Nicole P Sandhu, sandhu.nicole{at}


A healthy 27-year-old woman presented to an outside institution with unilateral nipple pruritus and a slight brown discolouration. When her symptoms failed to respond to topical therapy, nipple biopsy revealed Paget’s disease of the nipple. The patient sought further evaluation and care at our institution. Further investigation revealed multifocal breast cancer and the patient underwent bilateral mastectomies with sentinel lymph node biopsy followed by adjuvant systemic therapy. She is currently more than 4 years out from surgery and chemotherapy and has had no evidence of breast cancer recurrence.

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  • Competing interests None.

  • Patient consent Obtained.

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