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Optic nerve involvement as a first manifestation of acute lymphoblastic leukaemia after remission
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  • Published on:
    Optic nerve involvement in Acute Lymbhobastic Leukaemia , more than what meets the eye
    • Sunil R Moreker, Eye surgeon
    • Other Contributors:
      • Dr Gaurav Gupta , Saifee Hospital Mumbai India

    Acute Lymphoblastic Leukaemia can affect the eye in various ways . It may present with an ischaemic optic nerve involvement (1) or optic nerve swelling due to direct involvement . But sometimes it may also present as an optic nerve involvement as an effect of a drug like Linezolid which has been used for treatment of infections which coexist (2) or it may present as an infiltration of the nerve in combination with...

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    Conflict of Interest:
    None declared.
  • Published on:
    Interesting Case

    Editor Madam, it is very interesting case where the Lymphoblasts appeared to cross over the blood brain barrier to appear in the CSF or a leak from adjoining bone or capillary contributed it, and more interestingly blast cells in CSF spared rest of the brain and nerves while preferentially deposited in retinal layers formed by optic nerve, like of the previous cases cited in the report. If any other significant reason ap...

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    Conflict of Interest:
    None declared.