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Rare disease
Primary angiosarcoma of the bladder in a young female
  1. Richard R Warne1,
  2. Jeremy S L Ong2,
  3. Bret Snowball3,
  4. Justin B Vivian4
  1. 1Department of Radiology, Royal Perth Hospital, Perth, Western Australia, Australia
  2. 2Department of Dentistry and Health Sciences, University of Western Australia, Crawley, Western Australia, Australia
  3. 3Pathwest Laboratory Medicine Department, Queen Elizabeth II Medical Centre, Nedlands, Perth, Western Australia, Australia
  4. 4Department of Surgery, University of Western Australia, Crawley, Western Australia, Australia
  1. Correspondence to Dr Richard R Warne, Richard.Warne{at}


Our case report pertains to a 32-year-old woman initially presenting with left flank pain and gross haematuria throughout her urinary stream. CT of her kidney/ureter/bladder (CT KUB) revealed ureteric dilatation to the level of the bladder without evidence of renal calculus and subsequently a stent was inserted. She represented a month later with contralateral flank pain, and a transuretheral resection of bladder tumour was performed. Histopathological diagnosis was epithelioid angiosarcoma. Further imaging (MRI pelvis) revealed that the tumour arose from the posterior bladder wall with local invasion and regional lymph node metastasis. Ifosfamide and epirubicin chemotherapy with single-fraction radiotherapy induced significant reduction in tumour bulk, although this initial response was followed by the development of symptoms suggestive of disease progression. She died 19 months after initial diagnosis with persistent pulmonary and vertebral metastases although no autopsy was performed.

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  • Competing interests None.

  • Patient consent Obtained.

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