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Unusual presentation of more common disease/injury
A large swelling of the tongue
  1. Jay Gopal Ray1,2,
  2. Sourav Bhattacharya3,
  3. Basudev Mahato3,
  4. Sanjit Mukherjee2,
  5. Keya Chaudhuri2
  1. 1Department of Oral and Maxillofacial Pathology, Dr R Ahmed Dental College and Hospital, Kolkata, WestBengal, India
  2. 2Department of Molecular and Human Genetics, Indian Institute of Chemical Biology, Kolkata, West Bengal, India
  3. 3Department of Oral Pathology, Dr R Ahmed Dental College and Hospital, Kolkata, India
  1. Correspondence to Professor Jay Gopal Ray, jaygopalray{at}


Hyalinising clear cell carcinoma (HCCC) is an infrequent distinct histological subtype of clear cell adenocarcinoma encountered in minor salivary glands which can be confused with a variety of clear cell-rich tumours. The entity of HCCC should be considered in patients presenting with well-circumscribed longstanding nodular enlargement without any other significant abnormality. HCCC is often difficult to diagnose due to its unusual presentation. This report presents a male patient who reported with a complaint of 2 month history of a large swelling on the tongue. The clinical, radiological, histological and immunohistochemical findings, confirmed the diagnosis of HCCC.

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  • Competing interests None.

  • Patient consent Obtained.

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