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Rare disease
A report on a rare case of Klebsiella ozaenae causing atrophic rhinitis in the UK
  1. Yi Jie Lee1,
  2. Luke Stephen Prockter Moore2,
  3. John Almeyda1
  1. 1ENT Department, West Middlesex University Hospital, Middlesex, UK
  2. 2Microbiology Department, West Middlesex University Hospital, Middlesex, UK
  1. Correspondence to Mr Yi Jie Lee, yjlee{at}


Ozena is a chronic disease of the nasal cavity characterised by atrophy of the mucosa and bone caused by Klebsiella ozaenae. It is endemic to subtropical and temperate regions affecting the lower socio-economic group, usually the poor who live in unhygienic conditions. It is a rare disease in the UK. There is usually a delay in diagnosis due to unfamiliarity of the disease. A 25-year-old Nigerian migrant presented with nasal obstruction with purulent nasal discharge. Isolation of the bacterium was found from cultures of nasal discharge, crusting and tissue biopsies. She was treated successfully with ciprofloxacin. It is important to consider this rare condition in cases of nasal obstruction even in non-endemic areas especially with the advances of modern travel.

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  • Competing interests None.

  • Patient consent Obtained.

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