Statistics from Altmetric.com
In this case the lamina propria of the non-ulcerated gastric mucosa was densely infiltrated by epithelioid cells with significant cytological abnormalities. There was marked non-uniform karyomegaly, with irregular nuclear contours and frequent macronucleoli in the infiltrating cells. Some of these cells showed intracytoplasmic lumen formation strongly suggesting poorly differentiated signet ring cell carcinoma (figure 1).
However, careful scrutiny by microscope revealed red blood cells in a rare intracellular lumen and the immunoprofile (vimentin, CD 34 and factor VIII related antigen positive and pan-cytokeratin, CD68 and epithelial membrane antigen negative) confirmed the reactive mesenchymal-endothelial origin of these cells (figure 2).3
Competing interests None.
Patient consent Not obtained.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.