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Unusual presentation of more common disease/injury
Focal nodular hyperplasia with major sinusoidal dilatation: a misleading entity
  1. Hervé Laumonier1,
  2. Nora Frulio1,
  3. Christophe Laurent2,
  4. Charles Balabaud3,
  5. Jessica Zucman-Rossi4,
  6. Paulette Bioulac-Sage5
  1. 1Radiology Department, Hôpital St André CHU Bordeaux, Bordeaux, France
  2. 2Surgery Department, Hôpital St André CHU Bordeaux, Bordeaux, France
  3. 3Inserm, U889, Université Victor Segalen Bordeaux 2, Bordeaux, France
  4. 4Génomique Fonctionnelle des Tumeurs Solides, Paris, France
  5. 5Pathology Department, Hôpital Pellegrin, Place Amélie Raba Léon, Bordeaux, France
  1. Correspondence to Hervé Laumonier, herve.laumonier{at}


Focal nodular hyperplasia (FNH) is a benign liver lesion thought to be a non-specific response to locally increased blood flow. Although the diagnosis of FNH and hepatocellular adenoma (HCA) has made great progress over the last few years using modern imaging techniques, there are still in daily practice some difficulties concerning some atypical nodules. Here, the authors report the case of a 47-year-old woman with a single liver lesion thought to be, by imaging, an inflammatory HCA with major sinusoidal congestion. This nodule was revealed to be, at the microscopical level and after specific immunostaining and molecular analysis, an FNH with sinusoidal dilatation (so-called telangiectatic focal nodular hyperplasia).

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  • Competing interests None.

  • Patient consent Obtained.