Article Text

Reminder of important clinical lesson
A subcutaneous tumour in a patient with rheumatoid arthritis
  1. Karen Carlsen1,
  2. Pernille Leicht2,
  3. Henning Bliddal3
  1. 1Frederiksberg Hospital, Rheumatology, Nordre Fasanvej 57, Frederiksberg, 2000, Denmark
  2. 2Rigshospitalet, Hand Surgery, Blegdamsvej, Copenhagen, 2100, Denmark
  3. 3The Parker Institute, Frederiksberg Hospital, Frederiksberg, 2000, Denmark
  1. Correspondence to Henning Bliddal, hb{at}


A 79-year-old Caucasian woman with rheumatoid arthritis (RA) for 27 years presented with a swelling on her left wrist. Both pain and a tingling sensation in the radial four fingers could be elicited by applying light pressure on the swelling. The patient was uncertain as to the actual onset of this swelling and had not complained, as it resembled many of the swellings of the hand region she had previously experienced. Primarily, an organised tenosynovitis was suspected with a presumed pressure on the median nerve, and a puncture was considered. Ultrasonography diagnosed a large hypoechoic mass. This is not unusual with longstanding inflammatory changes, which may contain elements of connective tissue. Using the Doppler function it turned out to be highly vascularised. The tumour could not be removed, but histology revealed a diagnosis of schwannoma.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: None.

  • Patient consent: Patient/guardian consent was obtained for publication.