Article Text

Download PDFPDF

Unexpected outcome (positive or negative) including adverse drug reactions
Spontaneous regression in advanced non-small cell lung cancer
  1. Adam Gladwish1,
  2. Katy Clarke2,
  3. Andrea Bezjak2
  1. 1University of Toronto, Toronto, Ontario, Canada
  2. 2Radiation Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada
  1. Correspondence to Adam Gladwish, adam.gladwish{at}utoronto.ca

Summary

Locally advanced lung cancer, if untreated, typically progresses although the rapidity of progression may vary. The authors report the case of an 84-year-old woman who presented with radiologically progressive, biopsy proven stage IIIB (T2N3) squamous cell carcinoma in the left lower lobe of the lung. Her disease was too advanced for curative treatment and in view of the lack of symptoms to palliate, she received no anticancer treatment. In follow-up, her tumour was noted to spontaneously regress in size on serial chest x-rays. Eight months after biopsy, restaging CT showed complete resolution of the enlarged biopsy proven mediastinal and hilar lymph nodes and significant regression of the primary tumour. She remains clinically well.

View Full Text

Statistics from Altmetric.com

Footnotes

  • Competing interests None.

  • Patient consent Obtained.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.