Article Text

Download PDFPDF
Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
The serotonin syndrome as a result of mephedrone toxicity
  1. Gerard Garrett1,
  2. Michael Sweeney2
  1. 1School of Medicine, NUI Galway, Galway, Ireland
  2. 2Emergency Department, Sligo General Hospital, Sligo, Ireland
  1. Correspondence to Gerard Garrett, g.garrett2{at}


A 22-year-old male presented to an emergency department by ambulance. His clinical picture included tachycardia, diaphoresis, hypertonia, hyper-reflexia and clonus. The patient became hyperthermic and deteriorated over the next hour. The principal substance ingested was mephedrone and appropriate treatment for the serotonin syndrome resulted in a sustained recovery over 15 h.

Statistics from


  • Competing interests None.

  • Patient consent Obtained.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.