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Rare disease
Aortic homograft endocarditis caused by Cardiobacterium hominis and complicated by agranulocytosis due to ceftriaxone
  1. Dominique Braun1,
  2. Arthur Horovitz2,
  3. Mihai Bertea3,
  4. Rolf Jenni4,
  5. Huldrych F Günthard1
  1. 1Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland
  2. 2Private Practice, Zurich, Switzerland
  3. 3Institute of Medical Microbiology, University Hospital Zurich, Zurich, Switzerland
  4. 4Department of Cardiology, University Hospital Zurich, Zurich, Switzerland
  1. Correspondence to Dominique Braun, dominique.braun{at}


The present report describes a very rare case of an aortic homograft valve endocarditis caused by Cardiobacterium hominis. The case was complicated by an agranulocytosis after 3 weeks of antibiotic treatment induced by ceftriaxone. Alternative oral treatment with ciprofloxacin and rifampicin was successful, no surgical intervention was needed and homograft function could be preserved.

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  • Competing interests None.

  • Patient consent Obtained.

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