Article Text

Unusual association of diseases/symptoms
Thyroid swelling in a 32-year-old male
  1. Manoj Pandey1,
  2. Vinay Kumar1,
  3. Mridula Shukla2,
  4. Mohan Kumar2
  1. 1
    Institute of Medical Sciences, Surgical Oncology, Banaras Hindu University, Varanasi, UP, 221005, India
  2. 2
    Institute of Medical Sciences, Pathology, Banaras Hindu University, Varanasi, UP, 221005, India
  1. Manoj Pandey, manojpandey{at}


Patients with intrathyroidal metastasis may present with previous history of malignancy or they may present with a secondary neoplasm prompting us to search for the primary site. A 32-year-old male presented with a 4-month history of thyroid swelling and abdomen pain. Fine-needle aspiration cytology from the thyroid swelling revealed deposits from the mucinous adenocarcinoma. The further diagnostic and metastatic work-up identified a diffuse carcinoma of the stomach as the primary site with liver as secondary and retroperitoneal lymph nodes having mucinous deposits with associated Peutz-Jeghers polyposis. This is the first report in the English literature of intrathyroidal metastasis from carcinoma of the stomach with Peutz-Jeghers polyposis presenting primarily as a thyroid swelling. Preoperative diagnosis, proper evaluation and high degree of suspicion may avoid unnecessary thyroidectomy and effective palliation can be achieved with chemotherapy in view of disseminated disease.

View Full Text

Statistics from


  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.