Article Text

Rare disease
Rosai–Dorfman disease: sinus histiocytosis with massive lymphadenopathy
  1. Arif Sanli,
  2. Mehmet Eken,
  3. Zeynep Alev Oktay,
  4. Mustafa Paksoy,
  5. Umit Hardal
  1. ENT, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Istanbul, 34870, Turkey
  1. Mehmet Eken, memedeken{at}


A 25-year-old man presented with a 3 month history of a painless mass on the right side of his neck. Physical examination revealed a smooth surfaced, bilobed, 4×3 cm, semimobile mass at the right and 3×2 cm at the left jugulodigastric region. Endoscopic examination of the patient showed a granular tumour in both nasal cavities. After biopsies were taken from the mass from the nasal cavity, a diagnosis of Rosai–Dorfman disease was made. A conservative approach was taken to treatment and after the 6 month follow-up period, the patient was in a stable condition.

View Full Text

Statistics from


  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.