Article Text

Unusual association of diseases/symptoms
An unusual cause for fever of unknown origin in a patient with a prosthetic valve
  1. Ramanathan Parameswaran,
  2. Balavinoth Ramakrishnan,
  3. Mukhyaprana Prabu,
  4. Balasubramanian Ramachandran
  1. Kasturba Medical College, Internal Medicine, Madhav Nagar, Manipal, 576104, India
  1. Ramanathan Parameswaran, drram_82{at}


A case of Wegener granulomatosis as a cause for fever of unknown origin (FUO) and secondary involvement of endocardium in association with mitral valve prosthesis is presented. Although the patient was referred as a case of unresolving pneumonia, her unresponsiveness to broad spectrum antibiotics including infective endocarditis treatment prompted investigation for a non-infectious aetiology for her FUO, leading to a diagnosis of Wegener granulomatosis.

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  • Competing interests: None.

  • Patient consent: Patient/guardian consent was obtained for publication.