Article Text

Unusual presentation of more common disease/injury
Malignant hypertension complicated by acute renal failure
  1. Xiao Li,
  2. Wen Zhang,
  3. Hong Ren,
  4. Xiaoxia Pan,
  5. Nan Chen
  1. Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Nephrology, 197 Ruijin Er Road, Shanghai, 200025, China
  1. Nan Chen, chen-nan{at}


Malignant hypertension is closely associated with impairment of multiple organs, and renal dysfunction remains an important cause of morbidity and mortality in patients with malignant hypertension. The renal histopathological changes usually indicate malignant arteriolar nephrosclerosis (MANS) that is characterised by fibrinoid necrosis in small arteries. However, renal biopsies were not taken routinely in previous reports. We report an educational case of malignant hypertension caused by MANS leading to thrombotic microangiopathy (TMA).

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  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication.

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