Article Text

Rare disease
Lambert-Eaton myasthenic syndrome
  1. R Petty
  1. Southern General Hospital, Neurology, 1345 Govan Road, Glasgow, G51 4TF, UK
  1. richard.petty{at}


Lambert-Eaton myasthenic syndrome is a disorder of neuromuscular transmission in which an autoantibody is directed against the pre-synaptic calcium channel. It presents with proximal limb weakness, greater in the legs, with or without peripheral and autonomic neuropathy. Bulbar involvement is rare and fatigueability is not a feature.

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  • Competing interests: None.

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