Article Text

Rare disease
Primary leiomyoma of the liver: accurate preoperative diagnosis on liver biopsy
  1. Helena T Sousa1,
  2. Francisco Portela1,
  3. Luis Semedo2,
  4. Emanuel Furtado3,
  5. Carol Marinho4,
  6. Maria A Cipriano4,
  7. Maximino C Leitão1
  1. 1
    Department of Gastroenterology, Coimbra University Hospital, Praceta Mota Pinto, Coimbra 3000-075, Portugal
  2. 2
    Department of Radiology, Coimbra University Hospital, Praceta Mota Pinto, Coimbra 3000-075, Portugal
  3. 3
    Department of Surgery II, Coimbra University Hospital, Praceta Mota Pinto, Coimbra 3000-075, Portugal
  4. 4
    Department of Pathology, Coimbra University Hospital, Praceta Mota Pinto, Coimbra 3000-075, Portugal
  1. H T Sousa, helenatsousa{at}gmail.com

Summary

Primary leiomyoma of the liver is an exceptionally rare tumour in non-immunocompromised patients. Preoperative diagnosis of the lesion is difficult as complete imaging of this type of lesion is scarcely defined and preoperative biopsy was not the practice in previously reported cases. We report a voluminous primary leiomyoma of the liver occurring in a healthy middle-aged woman where a preoperative diagnosis was accurately achieved on biopsy. Because of its size, surgery was undertaken for exclusion of malignancy. A 16-month uneventful follow-up has been completed. We discuss the advantage of a preoperative diagnosis and propose that an imaging-guided liver biopsy should be undertaken, provided malignancy features are absent. This could prevent liver surgery merely for diagnostic purposes. Finally, we report imaging features that have not been previously described, namely on magnetic resonance imaging, which may provide an insight about the nature of this particular lesion and, advantageously, contribute toward a non-invasive diagnosis.

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Footnotes

  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication.

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