Article Text

Novel treatment (new drug/intervention; established drug/procedure in new situation)
Sacral neuromodulation enabling simultaneous pancreas and kidney transplantation: a first case
  1. Donatella Pistolesi1,
  2. Massimiliano Barsotti2,
  3. Gianluca Giannarini1,
  4. Mauro Mantovani3,
  5. Ugo Boggi4,
  6. Thomas M Kessler5,
  7. Cesare Selli1
  1. 1
    University of Pisa, Urology, Pisa, 56126, Italy
  2. 2
    University of Pisa, Transplantation Nephrology and Dialysis, Pisa, 56126, Italy
  3. 3
    Medtronic Italia, Sesto San Giovanni, Milan, 20099, Italy
  4. 4
    University of Pisa, General and Transplantation Surgery, Pisa, 56126, Italy
  5. 5
    The National Hospital for Neurology and Neurosurgery, Uro-Neurology, London, WC1N 3BG, UK
  1. gianluca.giannarini{at}


We report a case where simultaneous pancreas and kidney transplantation was precluded because of recurrent urinary tract infections due to non-obstructive chronic urinary retention requiring clean intermittent self catheterisation in a diabetic woman with end stage renal disease. Sacral neuromodulation restored voiding and cured recurrent urinary tract infections, enabling her to undergo simultaneous pancreas and kidney transplantation.

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  • Competing interests: Mauro Mantovani is an employee of Medtronic Italia, Milan, Italy. Thomas M. Kessler has acted as a consultant for Medtronic.

  • Patient consent: Patient/guardian consent was obtained for publication