Article Text

Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Corticobasal syndrome due to a thalamic tuberculoma and focal cortical atrophy
  1. K R Mridula1,
  2. S Alladi1,
  3. D R Varma2,
  4. J R Chaudhuri3,
  5. Y Jyotsna4,
  6. R Borgohain1,
  7. S Kaul1
  1. 1
    Department of Neurology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, India
  2. 2
    Department of Radiology, Krishna Institute of Medical Sciences, Minister Road, Hyderabad, India
  3. 3
    Department of Neurology, Kamineni Hospitals, LB nagar, Hyderabad, India
  4. 4
    Department of Radiology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, India
  1. alladisuvarna{at}


Corticobasal syndrome (CBS) is characterised by asymmetric apraxia, cortical sensory loss, extrapyramidal features and cognitive decline. Although CBS is classically described as a taupathy, heterogeneity of its aetiology is increasingly recognised. Clinical presentation of CBS appears to reflect areas of the brain involved and not necessarily the nature of the underlying pathology. We report a patient in whom resolution of a thalamic tuberculoma was associated with progressive atrophy of the parietotemporal cortex, resulting in an unusual presentation of CBS

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  • Competing interests: None.