Article Text

This article has a correction. Please see:

Unusual association of diseases/symptoms
Bilateral pulmonary nodules in an adult patient with bronchiolitis obliterans-organising pneumonia
  1. Antonios Kopanakis1,
  2. Christos Golias2,
  3. Michalis Patentalakis2,3,
  4. Christos Mermigkis3,
  5. Alexandros Charalabopoulos2,
  6. Dimitrios Peschos4,
  7. Anna Batistatou4,
  8. Konstantinos Charalabopoulos2
  1. 1
    Department of Intensive Care, Edessa State Hospital, Fidiou 9 Street, Edessa, 45500, Greece
  2. 2
    Medical Faculty, University of Ioannina, Department of Physiology, Clinical Unit, 13 Solomou Street, Ioannina, 45221, Greece
  3. 3
    Sismanoglion Hospital, Department of Occupational Lung Diseases and Tuberculosis, 13 Solomou Street, Ioannina, 45221, Greece
  4. 4
    Medical Faculty, University of Ioannina, Department of Pathology, 13 Solomou Street, Ioannina, 45221, Greece
  1. kcharala{at}


A 58-year-old male ex-smoker was admitted to hospital because of nodular infiltrates on chest x rays. He was complaining of fatigue, dyspnoea with exertion, low grade fever and weight loss. Physical examination was unremarkable. Bronchoscopy was inconclusive but revealed endobronchial lesions of chronic active inflammation. The diagnosis of cryptogenic organising pneumonitis bronchiolitis obliterans-organising pneumonia (COP-BOOP) was established by open lung biopsy. Proliferative bronchiolitis with regions of organising pneumonia is the characteristic feature of COP. The radiological picture of bilateral pulmonary nodules is an infrequent manifestation of COP. Lung biopsy, open or with video assistance thoracic surgery, is recommended to confirm the diagnosis.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication.