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  • Putaminal petechial haemorrhage as the cause of non-ketotic hyperglycaemic chorea: a neuropathological case correlated with MRI findings

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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Putaminal petechial haemorrhage as the cause of non-ketotic hyperglycaemic chorea: a neuropathological case correlated with MRI findings
  1. Tiago Mestre1,
  2. Joaquim Ferreira1,
  3. José Pimentel2
  1. 1
    Neurological Clinical Research Unit, Institute of Molecular Medicine, Av Prof Egas Moniz, Lisbon, 1649-028, Portugal
  2. 2
    Neuropathology Laboratory, Lisbon Medical School, Av Prof Egas Moniz, Lisbon, 1649-028, Portugal
  1. tmestre{at}gmail.com

Summary

Acute generalised chorea can be attributed to multiple causes, including non-ketotic hyperglycaemia. This cause has been associated with characteristic image signs of striatal hyperdensity on CT scan and hyperintensity on T1 weighted (T1W) MRI. We report a patient presenting with this syndrome in which a postmortem study was conducted. The findings of striatum petechial hemorrhages gives a significant contribution towards explaining the nature of the imaging signs observed in the syndrome of acute chorea associated with non-ketotic hypergycaemia.

https://doi.org/10.1136/bcr.08.2008.0785

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    Footnotes

    • Competing interests: None.