Article Text

Novel diagnostic procedure
Boerhaave syndrome: a diagnostic conundrum
  1. Matt Peter Wise1,
  2. Jonathan B Salmon2,
  3. Nick D Maynard2
  1. 1
    University Hospital of Wales, Adult Critical Care, Heath Park, Cardiff CF14 4XW, UK
  2. 2
    John Radcliffe Hospital, Adult Intensive Care, Headley Way, Headington, Oxford OX3 9DU, UK
  1. mattwise{at}


A 79-year-old man presented to the Emergency Department with abdominal pain 1 day after an elective total knee replacement. The patient was confused and drowsy, with a high fever, hypotension and uncontrolled atrial fibrillation. He subsequently developed respiratory failure, requiring admission to intensive care. It was then noted that a large pleural effusion had developed between two chest radiographs performed only 4 h apart. A pigtail catheter inserted into the pleural space revealed a transudate of pH 7.0 with an amylase of 17 220 U (serum amylase 54 U), and thus a diagnosis of spontaneous oesophageal rupture or Boerhaave syndrome was made. Despite drainage of the pleural space, the patient developed shock and multiorgan failure requiring mechanical ventilation, renal replacement therapy and cardiovascular support. The oesophageal leak was treated conservatively with intercostal tube drainage; the patient made a full recovery and was discharged from hospital 75 days later.

View Full Text

Statistics from


  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.