Article Text

Novel treatment (new drug/intervention; established drug/procedure in new situation)
A case of small cell carcinoma of the oesophagus treated with endoscopic mucosal resection who remained in clinical remission for 18 months: its endoscopic features with specific light spectra
  1. Toshie Nata1,
  2. Mikihiro Fujiya1,
  3. Hiroki Tanabe1,
  4. Nobuhiro Ueno1,
  5. Youkou Konno2,
  6. Chisato Ishikawa1,
  7. Yuhiei Inaba1,
  8. Takahiro Ito1,
  9. Ryu Sato2,
  10. Kentaro Moriichi1,
  11. Kotaro Okamoto1,
  12. Atsuo Maemoto3,
  13. Yusuke Mizukami1,
  14. Jiro Watari4,
  15. Toshifumi Ashida3,
  16. Yutaka Kohgo1
  1. 1
    Asahikawa Medical College, 3rd Department of Internal Medicine, 2-1-1-1 Midorigaoka Higashi, Asahikawa, 078-8510, Japan
  2. 2
    Engaru-Kosei General Hospital, Internal Medicine, 1-5 Oodori-kita 3chome, Engaru-cho, Monnbetsu-gun, 099-040, Japan
  3. 3
    Sapporo Higashi Tokushukai Hospital, IBD Center, 3-1 Kita 33jyo Higashi 14chome, Higashi-ku, Sapporo, 065-0033, Japan
  4. 4
    Hyogo College of Medicine, Hyogo, Kobe, 7, Japan
  1. Mikihiro Fujiya, fjym{at}


Small cell carcinoma of the oesophagus (SCCE) is an infrequent tumour associated with a poor prognosis. We herein propose the first case of SCCE treated by endoscopic mucosal resection (EMR) and its endoscopic images with narrow band imaging (NBI) and autofluorescence imaging (AFI). A 63-year-old man complained of a loss of appetite. An upper endoscopic examination revealed a 7 mm nodule located 33 cm from the incisors. A weakly stained area was shown by iodine staining. NBI detected brownish amorphous dots with irregular vessels on the surface of the nodule and AFI distinctly embossed the lesion magenta. A biopsy specimen obtained from the lesions revealed typical SCCE. The patient underwent EMR to remove the SCCE and thereafter remained in a state of clinical remission for 18 months. In summary, NBI and AFI may be useful for detecting and differentially diagnosing SCCE from the squamous cell carcinoma of the oesophagus. EMR is therefore considered to be a potentially useful therapeutic option for removing SCCE instead of performing an oesophagotomy.

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  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication

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