Article Text

Reminder of important clinical lesson
Precocious puberty and a sellar mass
  1. Anil Bhansali,
  2. P Jayaprakash,
  3. Pinaki Dutta,
  4. Rama Walia,
  5. P Ravikumar
  1. Endocrinology, Postgraduate Institute of Medical Education & Research, Chandigarh, 160012, India
  1. Anil Bhansali, anilbhansali_endocrine{at}


Precocious puberty in a child less than 3 years of age is usually gonadotropin dependent and is often associated with extrasellar central nervous system disorders. The present report describes the case of a 2½-year-old girl who presented with gonadotropin-independent precocious puberty and had a sellar mass. She was referred for neurosurgical intervention to our institute. On investigation, she was found to have primary hypothyroidism of autoimmune aetiology, which is rarely associated with precocious puberty and sellar mass due to thyrotroph hyperplasia. She was successfully treated with levothyroxine, and with this secondary sexual characteristics progressively regressed and the sellar mass disappeared.

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  • Competing interests: None.

  • Patient consent: Patient/guardian consent was obtained for publication.