Article Text

Reminder of important clinical lesson
Generating hand dysaesthesiae: the “GHD phenomenon” – straight to the diagnosis
  1. Roisin Lonergan1,
  2. Grainne Gorman1,
  3. Michael D Alexander1,
  4. Ronan Killeen2,
  5. Catherine de Blacam1,
  6. Niall Tubridy1
  1. 1
    St. Vincent’s University Hospital, Neurology, Elm Park, Dublin 4, Ireland
  2. 2
    St. Vincent’s University Hospital, Radiology, Elm Park, Dublin 4, Ireland
  1. Roisin Lonergan, roisin.lonergan{at}


Two Irish women presented with difficulty in completion of hair straightening, limited by upper limb dysaesthesiae due to claudication or brachial plexus entrapment induced by sustained shoulder abduction beyond 90 degrees. The first described arm pain precipitated by elevation and sustained abduction above shoulder level, particularly while using her GHD hair-straightener. Elevated arm stress test was positive and a left cervical rib was seen on chest x ray. Neurogenic thoracic outlet syndrome (TOS) was diagnosed and the cervical rib was resected. The second described arm tingling and weakness when performing tasks involving shoulder abduction and elevation, limiting GHD use to 10 min before having to rest. Upper limb blood pressure and pulses were undetectable. Erythrocyte sedimentation rate was elevated and flow on radial Doppler disappeared on abduction and elevation of each arm. A CT pulmonary angiography demonstrated features of Takayasu’s arteritis. Vascular TOS was diagnosed. Symptoms resolved with corticosteroids, followed by long-term immunosuppression and anti-coagulation.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Competing interests: none.

  • Patient consent: Patient/guardian consent was obtained for publication.