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Sub-acute blindness in a patient with a temporal lobe astrocytoma
  1. Ajai Seth1,
  2. Susan Short2,
  3. Fion Bremner3
  1. 1
    Queen Elizabeth Hospital, 12 Oakley Avenue, Barking, London IG11 9JD, UK
  2. 2
    UCL Hospital Foundation Trust, Oncology, 250 Euston Road, 1st Floor Central, London NW1 2PG, UK
  3. 3
    National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
  1. Ajai Seth, Oakley2654{at}


This report describes an unusual case of a middle-aged man who suffered sub-acute visual loss rendering him blind over a period of 4 weeks, associated with the diagnosis of a right temporal lobe World Health Organization grade 4 astrocytoma (glioblastoma multiforme). Chronic papilloedema had been diagnosed at presentation, and this persisted after his debulking surgery, but there was no radiological evidence of direct involvement (by compression or infiltration) of the visual pathways. This case report describes the sub-acute on chronic nature of his visual loss, and suggests possible causes and preventative measures for visual loss in these patients.

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  • Competing interests: none.

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