Article Text

Novel treatment (new drug/intervention; established drug/procedure in new situation)
Severe iron intoxication treated with exchange transfusion
  1. M Carlsson1,
  2. D Cortes3,
  3. S Jepsen2,
  4. T Kanstrup1
  1. 1
    Pediatric Intensive Care Unit, Odense University Hospital, Odense, Denmark
  2. 2
    Department of Pediatrics, Odense University Hospital, Odense, Denmark
  3. 3
    Department of Clinical Immunology, Odense University Hospital, Odense, Denmark
  1. Marcela Carlsson, marcelacarlsson{at}yahoo.dk

Summary

An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 µg/dl (244 µmol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 µg/dl (24 µmol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate.

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Footnotes

  • Competing interests: none.