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Rheumatology
Primary Sjogren’s syndrome presenting as hypokalaemic periodic paralysis and acute pancreatitis
  1. Santhosh Shettigere Chandrappa1,
  2. Pratap Kumar1,
  3. Prasan Kumar Panda1 and
  4. Shalinee Rao2
  1. 1General Medicine, All India Institute of Medical Sciences, Rishikesh, India
  2. 2Pathology and Lab Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
  1. Correspondence to Dr Prasan Kumar Panda; motherprasanna{at}rediffmail.com

Abstract

Renal tubular acidosis is a well-known consequence of primary Sjogren’s syndrome (pSS), but a rare manifestation similar to acute pancreatitis in pSS. Here, we discuss the case of a woman in her 50s, who presented to a tertiary care hospital with recurrent episodes of sudden-onset weakness in all four limbs, recurrent vomiting and epigastric pain. She had non-anion gap metabolic acidosis with hypokalaemia and was diagnosed with pSS with hypokalaemic periodic paralysis. She was also diagnosed with acute pancreatitis based on elevated amylase and lipase levels and CT findings. The article highlights the diverse spectrum of clinical manifestations of pSS, including renal and pancreatic involvements, which can be rare consequences of the disease.

  • Emergency medicine
  • Pancreatitis
  • General practice / family medicine
  • Muscle disease
  • Rheumatology

https://doi.org/10.1136/bcr-2024-260646

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    Footnotes

    • X @DrSanthosh_SC

    • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: SSC, PK, PKP and SR. The following authors gave final approval of the manuscript: SSC, PK, PKP and SR.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.