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Rheumatology
Yellow nail syndrome in anti-SSA and anti-SSB positive primary Sjögren’s syndrome
  1. Laura Jayne D'Adamo1,
  2. Yumi Oh2,3 and
  3. Laurel Young2,3
  1. 1Department of Internal Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia
  2. 2Department of Rheumatology, Redcliffe Hospital, Brisbane, Queensland, Australia
  3. 3Redcliffe Northside Rheumatology, Brisbane, Queensland, Australia
  1. Correspondence to Dr Laura Jayne D'Adamo; laura.dadamo2{at}health.qld.gov.au

Abstract

Yellow nail syndrome (YNS) is a rare, acquired condition, characterised by at least two of the three clinical criteria: nail changes, respiratory tract disease and lymphoedema. Currently, the aetiology of YNS remains unknown; however, it is believed to be caused by impaired lymphatic drainage. Currently, there remain no definitive treatment options available and no prospective trials evaluating this. Management includes supportive care and symptomatic treatment. The presence of YNS has been described alongside various conditions, including autoimmune diseases, malignancies and drug exposures. To strengthen the literature on this topic, we present the case of a female patient with a history of anti-SSA and anti-SSB positive primary Sjögren’s syndrome, who developed YNS in the immediate postpartum period.

  • Sjogren's syndrome
  • Rheumatology

https://doi.org/10.1136/bcr-2024-260614

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    Footnotes

    • Contributors LJD'A was responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content. LY and YO gave final approval of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.