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Post-infectious hydrocephalus complicating Listeria meningitis in a healthy newborn
  1. Saskia D'Sa1,
  2. Ezzeldin Saleh2,
  3. Subhash Chaudhary2 and
  4. Marcela Rodriguez2
  1. 1 Pediatrics, Southern Illinois University School of Medicine, Springfield, Illinois, USA
  2. 2 Pediatrics-Infectious Diseases, Southern Illinois University School of Medicine, Springfield, Illinois, USA
  1. Correspondence to Dr Marcela Rodriguez; mrodriguez{at}


Listeria monocytogenes is a relatively uncommon cause of foodborne infection in the general population. Most cases of Listeriosis occur among newborns, pregnant women, the elderly and those with impairment of cellular immunity. Neonatal Listeria meningitis is rare. We present a case of Listeria meningitis at the age of 15 days in a previously healthy neonate who presented with acute onset of fever, poor feeding and lethargy. Sepsis workup revealed L. monocytogenes identified in cerebrospinal fluid PCR and culture. The infant’s course was complicated by transient syndrome of inappropriate antidiuretic hormone and subsequent hydrocephalus that required a ventriculoperitoneal shunt placement. Though rare, neonatal infections due to Listeria can present with meningitis leading to serious and devastating complications. Our case emphasises the importance of considering Listeria in cases of neonatal meningitis and the value of close follow-up of such cases through early detection and management of acute and long-term complications.

  • Meningitis
  • Infectious diseases
  • Hydrocephalus
  • Materno-fetal medicine
  • Infections

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: SD drafted the initial manuscript, obtained images, collected pertinent data and reviewed and revised the manuscript. SD, MR and ES performed the relevant literature search and review. ES, MR and SC reviewed and revised the manuscript. ES, MR and SC contributed to case management. The following authors gave final approval of the manuscript: All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.