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Central toxic keratopathy leading to epithelial ingrowth following femtosecond LASIK
  1. Pratik Yeshwant Gogri1,
  2. Pravin Krishna Vaddavalli2 and
  3. Sushank Ashok Bhalerao3
  1. 1Cornea and Anterior Segment, Agarwal Eye Hospital, Navi Mumbai, India
  2. 2Shantilal Shanghvi Cornea Institute (SSCI), L V Prasad Eye Institute,Kallam Anji Reddy (KAR) Campus, Hyderabad, Telangana, India
  3. 3Shantilal Shanghvi Cornea Institute (SSCI), L V Prasad Eye Institute, Kode Venkatadri Chowdary (KVC) Campus, Vijayawada, Andhra Pradesh, India
  1. Correspondence to Dr Sushank Ashok Bhalerao; sushank55555{at}


We report a case of a woman in her 30s who underwent femtosecond LASIK (laser-assisted in situ keratomileusis) in both eyes to correct her simple myopic astigmatism. After the surgery, both eyes developed diffuse lamellar keratitis, and intensive topical steroids were initiated to control the same. Subsequently, central toxic keratopathy (CTK) developed bilaterally. Three weeks after the surgery, the right eye showed signs of progressive epithelial ingrowth involving the pupillary area. Surgical intervention in the form of flap relift followed by debridement of the epithelial cells and an alcohol interface wash were performed to treat the same. This is the first report of an epithelial ingrowth following CTK after femtosecond LASIK.

  • Anterior chamber
  • Iris

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content—PYG, PKV and SAB. The following authors gave final approval of the manuscript—PYG, PKV and SAB.

  • Funding This study was funded by Hyderabad Eye Research Foundation (grant number: 2023-05).

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.