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Delayed targeted atelectasis in a case of bronchoscopic lung volume reduction with endobronchial valves
  1. Nikitha C Chandra1,
  2. Isabel Fernandez-Bussy2,
  3. Katherine L Walsh1 and
  4. David Abia-Trujillo1
  1. 1 Division of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic in Florida, Jacksonville, Florida, USA
  2. 2 Pontificia Universidad Católica Argentina, Buenos Aires, Buenos Aires, Argentina
  1. Correspondence to Dr Nikitha C Chandra; chandra.nikitha{at}


A woman in her late 60s with severe chronic obstructive pulmonary disease (COPD) and emphysema underwent bronchoscopic lung volume reduction (BLVR) with endobronchial valves (EBV) to address hyperinflation. The initial EBV placement has led to partial lobar atelectasis of the left lower lobe and resulted in significant improvement in the patient’s symptoms and lung function. However, valve migration occurred later due to pneumothorax unrelated to valves, leading to suboptimal clinical improvement. The patient achieved delayed full lobar atelectasis 21 months after EBV placement, which led to a significant clinical improvement. The patient decided to be delisted from the lung transplant list due to the improvement. This case highlights the importance of considering delayed atelectasis as a possible outcome of EBV placement and suggests the need for further exploration of the long-term implications and associations of this procedure.

  • Pneumothorax
  • Respiratory medicine
  • Air leaks
  • Lung function

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  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: NCC performed the literature review, collected the patients’ medical data and wrote the original draft. IF-B performed the literature review. KLW performed the literature review and collected medical data. DA-T initiated the idea of submission, edited the images and revised the manuscript. All authors have approved the manuscript. The following authors gave final approval of the manuscript: NCC, IF-B, KLW, DA-T.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.