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Peritoneal tuberculosis: the diagnostic challenge must not preclude treatment
  1. Isabel Marques Correia1,
  2. Regina Costa1,
  3. Joana Inês Martins Madeira2 and
  4. Isabel Fonseca1
  1. 1Internal Medicine Department, Coimbra University Hospital Centre, Coimbra, Portugal
  2. 2Pathology Department, Coimbra University Hospital Centre, Coimbra, Portugal
  1. Correspondence to Dr Isabel Marques Correia; isabelmmcorreia{at}gmail.com

Abstract

Peritoneal tuberculosis (TB) is a rare extrapulmonary infection caused by Mycobacterium tuberculosis. It is mainly found in countries with a high burden of TB, so travelling from an endemic area should raise suspicion. Although it is a well-recognised disease, it remains a challenge due to its difficult clinical and microbiological diagnosis. This can lead to a delay, both in diagnosis and treatment with serious prognostic implications. We describe the case of a woman in her mid-50s who presented with fever, abdominal pain, vomiting, breathlessness, anorexia and weight loss. On physical examination, she had decreased breath sounds at the right lung and clinical ascites. Blood tests revealed elevated inflammatory markers and anaemia. Imaging showed ascites, enhanced peritoneal thickening, densification of the mesenteric fat and right pleural effusion. After paracentesis, diagnostic thoracotomy and laparoscopy were undertaken. Based on a presumptive diagnosis, treatment was started. M. tuberculosis was lastly isolated in ascitic fluid culture after 6 weeks. The patient completed a 6-month course of anti-TB drugs with a favourable outcome.

  • Tuberculosis
  • Infection (gastroenterology)

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Footnotes

  • Contributors All authors were involved in the clinical care of the patient. IMC performed the literature review, drafted the text and selected and edited the images. IMC, RC and IF critically revised the manuscript for important intellectual content. JIMM made the histological diagnosis and selected and described the peritoneal biopsy image. All authors approved the final version of the manuscript. IMC is responsible for the overall content as the guarantor.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.