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Autologous faecal microbiota transplantation via double barrel stoma to treat chronic diversion colitis
  1. Joseph Man Fung Tang,
  2. Fatmaalzahra Habib,
  3. Muhammad Rahmdil and
  4. Nikolaos Apostolou
  1. Gastroenterology, Southport and Ormskirk Hospital NHS Trust, Southport, UK
  1. Correspondence to Dr Joseph Man Fung Tang; joseph.tang2{at}merseywestlancs.nhs.uk

Abstract

Diversion colitis is a common phenomenon affecting patients after defunctioning ileostomy. We present a complex case of diversion colitis where the patient was deemed unsuitable for restorative surgery due to multiple areas of stricturing in a long defunctioned colonic segment. Despite initial treatments with rectally administered topical mesalazine, butyrate enemas and topical steroid therapy, the patient remained symptomatic with rectal bleeding and mucus discharge. Furthermore, the appearance of colitis could be appreciated on endoscopy and radiological investigations with changes in histology consistent with moderate–severe diversion colitis. This article describes our experience in the use of autologous faecal transplant administered via the efferent loop of a double-barrel ileostomy to successfully treat diversion colitis refractory to standard topical therapy.

  • Inflammatory bowel disease
  • General surgery
  • Gastrointestinal system
  • Gastroenterology

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Footnotes

  • Contributors I can confirm that the authors stated contributed substantially to the article. NA was responsible for overseeing the project and he performed all the endoscopy examinations and will act as guarantor for this article. FH and MR contributed to data collection and provided follow-up for the study patient. JMFT was responsible for the planning of the project and was involved in all aspects of the patient’s care including endoscopy, outpatient follow-up and write-up of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.