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Abstract
Tuberculosis is a global disease and presents with an array of neurological manifestations. Presentation varies from meningitis, radiculo-myelitis, tuberculoma, brain abscess and other combinations. The association of Guillain-Barre’ syndrome (GBS) with tuberculosis has been reported in a few reports. Neurological tuberculosis association with GBS is very rare. We here report an early adolescent patient with tubercular meningitis and tuberculoma who presented with acute areflexic quadriparesis and was subsequently diagnosed as an acute motor sensory axonal neuropathy variant of GBS. The diagnosis was confirmed with clinical examination, nerve conduction studies, positive anti-ganglioside antibody and clinical response to intravenous immunoglobulin. We present a case of an association between tubercular meningitis clinically presenting as encephalopathy and acute flaccid weakness due to GBS.
- Tuberculosis
- Pediatrics
- Neuromuscular disease
- Infection (neurology)
- Paediatric intensive care
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Footnotes
Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms and critical revision for important intellectual content: SV, SS and VMA. The following author gave final approval of the manuscript: MRS. MRS is the guarantor for all content and verification of data to be true.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.