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Caffey disease in an infant
  1. Anupama Tandon1,
  2. Fozia Raza1,
  3. Rajesh Tandon2 and
  4. Anwer Alam3
  1. 1Radiodiagnosis, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India
  2. 2Pathology, Holy Family Hospital, New Delhi, India
  3. 3Paediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India
  1. Correspondence to Dr Fozia Raza; foziaraza9{at}gmail.com

Abstract

A previously healthy female infant was brought to the paediatrics outpatient department by her mother reporting increased irritability and swelling behind her left shoulder, accompanied by restricted movement in her left arm. The irritability had been present for the past 5 months, with swelling also noticed at that time, gradually increasing in size. On examination, a large, firm, immobile mass was detected on the left scapular region. The mass was tender to touch, without any hardening or induration of the overlying skin. The child was afebrile, and her vital signs were stable. Subsequent imaging revealed hyperostosis in the left scapula, along with swelling of the surrounding soft tissue. After ruling out conditions such as chronic osteomyelitis, Ewing’s sarcoma, rhabdomyosarcoma, trauma or child abuse, chronic recurrent multifocal osteomyelitis and hypervitaminosis A, the findings pointed to Caffey disease. Although infantile cortical hyperostosis, or Caffey disease, is rare, it should be considered in the differential diagnosis of a bony swelling in a young child.

  • Paediatrics
  • Pathology
  • Radiology
  • Vitamins and supplements
  • Musculoskeletal and joint disorders

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Footnotes

  • Contributors The following authors were responsible for drafting of the text, sourcing and editing of clinical images, investigation results, drawing original diagrams and algorithms, and critical revision for important intellectual content: FR and AT. FR and AT are the guarantors. The following authors gave final approval of the manuscript: AT, FR, RT and AA.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.