Article Text

Download PDFPDF
Role of neurorehabilitation in the recovery of bilateral thalamic stroke related to the artery of Percheron anatomical variant
  1. Gaetano Polito1,
  2. Mirella Russo2,
  3. Matteo Santilli1,
  4. Cristina Cantarella3,
  5. Carlo D'Aurizio3 and
  6. Stefano L Sensi4
  1. 1Department of Neuroscience, Imaging and Clinical Science, Università degli Studi Gabriele d'Annunzio Chieti Pescara, Chieti, Italy
  2. 2Department of Neurosciences, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy
  3. 3AUSL Pescara, Pescara, Italy
  4. 4CeSI-MeT, Center for Excellence on Aging and Translational Medicine, University “G. d’Annunzio” Chieti-Pescara, Chieti, Italy
  1. Correspondence to Professor Stefano L Sensi; ssensi{at}


Bilateral thalamic stroke is a rare condition, mostly related to the presence of the artery of Percheron (AoP) variant. The clinical presentation of AoP-related strokes is remarkably heterogeneous and often includes cognitive and behavioural alterations. Our report describes the clinical course of an AoP-related bilateral thalamic stroke and highlights the pivotal role of a tailored rehabilitation programme plays in enhancing recovery. A man in his 40s was admitted to the neurology ward due to the abrupt onset of mental status alterations and weakness in his left limbs. The first brain CT scan and subsequent MRI exam revealed a bilateral thalamic stroke and the presence of an AoP anatomical variant. After the first critical phase, the patient’s condition became stable, but he still suffered from severe attention, memory and speech deficits. The patient was then transferred to the rehabilitation unit and was subjected to a tailored neurorehabilitation programme that allowed a complete recovery of the symptoms. Neurorehabilitation plays a pivotal role in the patient’s recovery and should always be pursued to minimise the residual deficits and, most importantly, to prevent permanent cognitive deficits.

  • Neuroimaging
  • Stroke
  • Memory Disorders

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors Patient’s management: GP, SLS, MR, MS, CC and CD'A. Design and application of the neurorehabilitation program: CD'A and CC. Neuropsychological evaluation: MS. Manuscript preparation: GP, MS, MR and SLS. Critical revision: SLS.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.